Abstract

In October 1991 the GEFI (Gruppo Ematologi Forensi Italiani) proposed a collaborative study on the use of AmpliType HLA-DQα Forensic DNA Amplification and Typing Kit (Parkin Elmer Cetus) for individual typing at the HLA-DQA1 locus (six alleles). The general recommendation for each participating group was to choose for the analysis a sample of at least 50 unrelated individuals, resident in the laboratory region. Five blind control samples from the Tenth International Histocompatibility Workshop were forwarded to each group. Twenty-three laboratories sent results in the deadline (see list below). We show here an analysis of the genetic heterogeneity between samples. A laboratory sent a selected subsample from its database and was excluded. The total number of considered individuals was 1623.

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