An Ion Cyclotron Resonance Study of an Organic Reaction Mechanism

Abstract

The detailed mechanisms of organic reactions in solution have preoccupied physical chemists for several decades. In the case of reactions postulated to occur via ionic intermediates in solution a great deal of mechanistic information may be obtained by a study of gas phase ion molecule processes for analogous systems. Ion cyclotron resonance spectroscopy has been shown to be particularly useful in this respect since the techniques of ICR single and double resonance and ion trapping are especially well suited to the eludication of reaction pathways1–3. Since gas phase ion-molecule reactions avoid the complicating of ion-solvent interactions the intrinsic reactivity and thermochemical stability of reactants and products may be determined. By further contrasting analogous solution and gas phase processes it is frequently possible to assess the role of the solvent in the reaction.KeywordsProton AffinityAcetyl ChlorideProtonated SpeciesAcyl HalideAcyl CationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.