Abstract

Astrocytes, also described as astroglia, are characteristic star-shaped glial cells in the brain. The important roles of astrocyte such as extracellular regulation, synaptic information regulation, neuronal synchronization and feedback to neural activity, makes the astrocytes play a vital role in the brain disease. This paper investigates the neuron–astrocyte interaction system for evaluating the network behaviors. In this approach, two basic systems are presented for considering the astrocyte controlling effects on desynchronization of the neurons spiking activity. Simulation results proved that by proper selection of the astrocyte coupling parameters in the proposed network, the networking behaviors can be modulated. As a result, when these coupling parameters have suitable values, the neurons behavior in the sample system will be controlled.

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