Abstract
An investigation of the direct compression properties of pre-gelatinized African bitter yam and cassava starches in acetylsalicylic acid tablet formulations
Highlights
IntroductionApart from being a common carbohydrate in diets, it is widely used in the pharmaceutical industries as excipients in tablet formulation as disintegrants, binders or lubricants
Starches are polysaccharides which serve as energy storage for most green plants
The powder of the African bitter yam starch was offwhite in colour while that of cassava starch was white
Summary
Apart from being a common carbohydrate in diets, it is widely used in the pharmaceutical industries as excipients in tablet formulation as disintegrants, binders or lubricants These roles of starch in tablet formulations have initiated a search for newer starches of natural origin and their modified improved varieties (Kottke et al, 1992; Odeku et al, 2009; Eraga et al, 2016). African bitter yam (Discorea dumetorum) is a root crop that grows in various parts of West Africa and it is popular in the south eastern part of Nigeria. It is cultivated in times of food scarcity or famine as a result of scarcity of other varieties of yam. This study is aimed at investigating the direct compression property of pre-gelatinized starches sourced from African bitter yam and cassava for direct compression of acetylsalicylic acid tablets
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