Abstract
Male rats were administered a free-feeding test under one of nine combined conditions of amphetamine (0.0, 0.5, 1.0 mg/kg) and food deprivation (0, 24, 48 h). Overall results demonstrated a significant drug effect and deprivation effect on feeding. Further analysis of the drug’s action under each of the motivational conditions demonstrated that the depressant effect of amphetamine was generalized over the range of motivational conditions studied and that the pattern of the dose-response function was quite similar.
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