An Investigation of 2D Spine Magnetic Resonance Imaging (MRI) with Compressed Sensing (CS).

Abstract

To investigate the feasibility of compressed sensing MRI (CS-MRI) in the application of 2D spinal imaging and compare its performance with conventional MR imaging (non-CS-MRI). The CS imaging protocol was optimized on 5 volunteers. Non-CS-MRI and CS-MRI of 2D sagittal T1 weighted imaging (WI), Sag T2WI, and axial T2WI were performed for 71 patients (22 cervical, 8 thoracic, 41 lumbar MRI). Paired t tests were conducted to compare the total scan time. Three radiologists assessed image quality and lesion diagnosis independently. A Kendall W test was performed to assess interobserver agreement of the image quality scores and lesion diagnosis between readers. A nonparametric test (Wilcoxon test) was performed to compare the image quality. For lesion diagnosis, the interobserver and interstudy agreements were evaluated by kappa analysis. Paired t tests were conducted for SNR and CNR comparison. The mean scan time for spine CS-MRI (4min 28.7s ± 34.6s) was significantly shorter than that with non-CS-MRI (7min 21.3s ± 38.7s, t = - 47.464, P < 0.0001). CS-MRI achieved higher SNR and CNR than Non-CS-MRI in image quality assessment. Interobserver agreements of lesion diagnosis were excellent between non-CS-MRI and CS-MRI (kappa value from 0.913 to 1.000, P < 0.001). Interstudy agreements of lesion assessments were also excellent (kappa value = 1.000, with P < 0.001). CS-MRI spine imaging can significantly reduce the scan time, while maintaining comparable imaging quality to non-CS-MRI.