Abstract

hERG (human Ether-à-go-go Related Gene) is a gene that encodes the pore-forming α-subunit of a voltage-gated potassium K+ channel expressed in the heart and in nervous tissue [1]. It is responsible for channels mediating the 'rapid' delayed rectifier K+ current (IKI) which plays a critical role in ventricular repolarisation phase of the cardiac action potential [2].

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