Abstract
Dermoscopy is a convenient tool to diagnose melanocytic lesions, especially nevus and melanoma. Various pigmented structures, including pigment network, dots and globules, and streaks, are observed in dermoscopy. Usually, 2D vertical images are used to explain the correlation of dermoscopy and histopathology. However, because the image of dermoscopy is horizontal, it is difficult for the horizontal view of dermoscopy to refer to the vertical view of histopathology. In our study, we digitally reconstructed 2D horizontal top-down view images and 3D aerial images from 50–100 serial 2D vertical sections by using high-speed scanner and 3D software in 6 cases of melanocytic lesion. Our new technology intuitively explained the histopathological structures corresponding to the dermoscopic structures. This technique could be used as a good educational tool for beginners.
Highlights
ResultA total of 6 pigmented skin lesions were observed in this study
Dermoscopy is a convenient tool to diagnose melanocytic lesions, especially nevus and melanoma
Dermoscopy is an optical observation device, by which we examine the detail of minute structures of melanocytic skin lesions
Summary
A total of 6 pigmented skin lesions were observed in this study. 1 Reed nevus, 1 Miescher nevus, 2 lentigo maligna melanoma (LMM; LMM1 and 2) and 1 superficial spreading melanoma (SSM). Quantities of serial sections were 100 in Miescher nevus, LMM2 and SSM, 70 in Spitz nevus and LMM1, and 50 in Reed nevus, respectively.
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