An Introduction to Drug Synthesis

Abstract

An Introduction to Drug Synthesis explores the central role that organic synthesis plays in the process of drug design and development. Part A of the book introduces major concepts and begins by outliningfirstly looks at the drug discovery process. Other chapters in the first part of the text then examines topics such as drug synthesis, retrosynthesis, cycliccycle systems in drug synthesis, and the synthesis of chiral drugs. There is also a chapter on combinational and parallel synthesis. Part B of the book moves on to consider the applications of drug synthesis in the drug development process and. This includes chapters on the synthesis of lead compounds, analogue synthesis in drug design, synthesis of natural products, chemical and process development, and synthesis of isotopically labelled compounds. The final partPart C, the final part of the text, looks at the design and synthesis of selected antibacterial agents.