Abstract
Based upon a radical polar effect, an intermolecular azidoheteroarylation of simple alkenes via a metal-free radical multicomponent cascade process was achieved. It allows a mild, rapid, and step-economic access to a broad range of azidoalkylated heteroaromatics. Given the diversity in transformations of organic azides and medicinally privileged scaffolds of heteroarenes, this strategy enables efficient synthesis and late-stage derivatization of drugs and candidates.
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