An Interesting and Highly Efficient Route to 2-(Arylethynyl)Selanyl-Azoles: Fe3O4-Serine-CuI Nanocomposite Catalyzed Three-Component Coupling Reaction of Azoles, Se Powder, and Alkynes

Abstract

2-(arylethynyl)selanyl-azoles are important and vital compounds that both azoles and aryl ethynyl selenides presented in their structure. In this article, we have constructed copper (I) iodide supported on the surface of magnetic Fe3O4 nanoparticles functionalized with Serine [Fe3O4-Serine-CuI] and evaluated its catalytic behavior in the preparation of 2-(arylethynyl)selanyl-azoles though one-pot three-component coupling reaction of azoles, Se powder and alkynes under ecofriendly conditions. The structure of Fe3O4-Serine-CuI nanocatalyst is well analyzed by several spectroscopic techniques like: FT-IR, SEM, EDX, TEM, MAP, XRD, TGA, VSM, ICP-OES techniques. High reusability and well characterization of Fe3O4-Serine-CuI nanocatalyst, high purity and yields of products, ecofriendly conditions, and simple operation are several considerable advantages this catalytic system.