An Intensive Care Unit Outbreak of Acute Respiratory Distress Syndrome due to Human Metapneumo Virus Infection

Ankur Sinha,Parita Soni,Yu Shia Lin,Namrita Malhan,Vignesh Ponnusamy,Hitesh Raheja,Yizhak Kupfer,Ravikaran Patti,Sushilkumar S Gupta

doi:10.1177/2324709619860549

Abstract

Human metapneumo virus is an emerging cause of upper and lower respiratory tract illness with increasing reports of a varied spectrum of disease over all age groups. We report an outbreak of 6 cases of human metapneumo virus infection in the intensive care unit of a metropolitan tertiary care center over 6 weeks, leading to severe acute respiratory distress syndrome. We report the subsequent favorable outcomes due to the institution of extracorporeal membrane oxygenation.

Highlights

Human metapneumo virus is an emerging cause of upper and lower respiratory tract illness
We report our findings while managing an outbreak of Human metapneumo virus (hMPV) in the medical intensive care unit (ICU) of a metropolitan referral center with 6 cases of acute respiratory distress syndrome (ARDS) over a period of 6 weeks
The peak incidence was found to be in early spring, slightly later than the outbreak period of the respiratory syncytial virus.[4] hMPV circulation follows a seasonal pattern with a biennial distribution from November to February and from April to July.[5]

Summary

Introduction

Human metapneumo virus (hMPV) is an emerging cause of upper and lower respiratory tract illness. We report our findings while managing an outbreak of hMPV in the medical intensive care unit (ICU) of a metropolitan referral center with 6 cases of acute respiratory distress syndrome (ARDS) over a period of 6 weeks. A respiratory culture and smear was performed for all patients in addition to a rapid viral panel on the day of presentation. Length of Radiography of ARDS Blood Culture Smear Intubation ECMO ICU Stay Outcome. Blood culture was positive for coagulase-negative Staphylococcus in 1 patient, this patient had a negative respiratory culture. Out of these 6 patients with ARDS, 66% (4 patients) needed intubation. All 5 patients who survived the disease continued to do well on a 1-year follow-up

Discussion

Findings

Conclusions