Abstract

Retinal imaging plays a very significant role in the study of retinal vasculature changes indicative of chronic disease information related to vision. This study investigates the invulnerability of retinal image information in the disease information system and assesses the quantitative method of the morphological changes in the retinal vascular network. In this work, the medical digital image transmission protocol Digital Imaging & Communications in Medicine (DICOM) version 3.0 and the retinal image Picture Archiving & Communication System (PACS) were constructed in the laboratory using browser/server mode. Also, the DICOM-SR document was designed in this article using a list or hierarchy, and the retinal images to report the information of patients by using the Hypertext Transfer Protocol (HTTP) – based Web Access to DICOM Persistent Objects (WADO) approach. The results showed that the retinal image PACS system constructed in Browser/Server mode can effectively store and transmit DICOM images. When the imaging device is combined with the application program, special adapters are used to negotiate the transmission syntax. The message flow is decoded in the communication process, which can be connected with the realization to improve the efficiency of information collection. The proposed PACS system integrates the quantitative features of retina providing more meaningful research data for data mining in comparison to the traditional state of the art methods based on chronic disease management system. The diagnostic ability of the retinal imaging procedure using the DICOM images is justified by obtaining 98.51%, 98.04%, 99% and 99.01% of accuracy, sensitivity, specificity and precision values respectively.

Highlights

  • Clinical retinal digital images are usually obtained by digital ophthalmoscopy, which is taken by a special camera through the pupil

  • The analysis done in this work for the investigation of invulnerable retinal imaging information can be used for quantitative analysis of morphological change of retinal vascular network

  • This work is mainly focused on the medical digital image transmission protocol Digital Imaging and Communications in Medicine (DICOM) version 3.0 and the retinal image Picture Archiving and Communication System (PACS) was constructed in the laboratory

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Summary

Introduction

Clinical retinal digital images are usually obtained by digital ophthalmoscopy, which is taken by a special camera through the pupil. The effectual retinal image management and storage is effective for the recognition of chronic diseases like Glaucoma, Diabetic retinopathy, macular degeneration and many more [5,6]. Different researches thrived for devising various diagnostic and image recognition systems for retinal image classification, management and storage. In order to solve the problem of registration of retinal images with different Angle of view of the retinal camera, Zou Beji et al proposed a local feature registration method with affine invariability [11]. The experimental results in the private sample set containing 83 sets of retinal images showed that the root-meansquare error of this method was 1.247±0.251 pixels, which could well solve the problem of perspective and scale change [14].

Retinal image web-PACS and design of DICOM-SR
Retinal vascular segmentation and arteriovenous classification
Quantitative analysis of retinal vascular tortuosity
Quantitative analysis of retinal vessel width
Quantitative analysis of retinal blood vessels
Materials and methods
Design of DICOM-SR for retinal vascular images
Fundus image prepossessing
Extraction of optic disc in retinal images
Retinal image report transmission based on WADO protocol
Retinal image Web-PACS
Access and display of retinal image DICOM-SR
Evaluation Parameters Recognition Value
Discussion and summary
Conclusions
Full Text
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