An Intelligent Computer Aided Diagnosis System for Classification of Ovarian Masses using Machine Learning Approach

Abstract

Ovarian cancer, a difficult and often asymptomatic malignancy, remains a substantial global health concern in women. An ovary is a female reproductive organ, which lies on each side of the uterus and used to store eggs. Computer-aided diagnosis (CAD) is an approach that involves using computer algorithms and machine learning techniques to assist medical professionals in diagnosing ovarian malignancies, benign tumors or Poly-cystic ovaries (PCOS). The need for models that can effectively predict benign ovarian tumors and ovarian cancer has led to the use of machine learning techniques. Our research objective is to propose a machine learning-based system for accurate and early ovarian mass detection utilizing novel annotated ovarian masses. We have used an actual patient database whose input features were extracted from 187 transvaginal ultrasound images from database. The input image is preprocessed using the Block Matching 3D filter. The process involves employing binary and watershed segmentation techniques, followed by the integration of Gabor, Gray-Level Co-Occurrence Matrix (GLCM), Tamura, and edge feature extraction methods. K-Nearest Neighbors (KNN) and Random Forest (RF) are two classifiers used for classification. Based on our results, we are able to demonstrate that binary segmentation with RF classifiers is more accurate (above 86%) than KNN classifiers (under 84%).