Abstract
Dopamine is very important neurotransmitter and the rapid and effective methods for its determination are of great importance in fundamental medical research. A rapid voltammetric assay for dopamine (DA) detection in presence of ascorbic acid (AA) based on an electrochemically pretreated pencil graphite electrode has been investigated. Differential pulse voltammetry results showed two well-distinguished oxidation peaks for DA and AA at 0.369 V and 0.142 V, respectively, and the method was applied for DA determination without previous separation. The obtained detection limit for DA was 5.17 � 10-8 M. The method has been successfully applied for determination of DA in a pharmaceutical sample.
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