An Integrated Brain ECVT and EEG System for Epilepsy Imaging

Abstract

Localization of epileptogenic area is a fundamental step in pre-surgical evaluation. Unfortunately, phase II EEG approach has high risk due to invasiveness like infection and bleeding. Therefore, alternative approach with attention to non-invasiveness, real-time measurement and mobility is urgently needed. Brain ECVT is believed to be one of the promising neuroimaging techniques to record human’s brain activities. In this study, we investigated the feasibility of integrated EEG and brain ECVT system. A twoelectrode Brain ECVT sensor was designed to facilitate a simultaneous measurement with EEG by using COMSOL software, phantom experiment and measurement with real human in resting-state condition. Visual and power spectral density (PSD) analysis showed that ECVT excitation at 100 Hz frequency or higher does not interfere with EEG measurement. Arithmetic task was performed in human subject experiment which shows that the signal PSD during the task is higher than during relax condition in both Brain ECVT and EEG measurements. ECVT excitation at 100 Hz or higher does not interfere with EEG measurement. Brain ECVT and EEG simultaneous measurement can give similar results based on the signal power spectral density analysis.