Abstract
Biological macromolecules are asymmetric structures. As such, they interact differently with left and right circularly polarized light. Circular dichroism (CD), the differential absorption of left and right circularly polarized light, probes changes in the secondary and tertiary structure of molecules in solution. Circular intensity differential scattering (CIDS), which is the differential scattering of left and right circularly polarized light, probes the higher order structure of macromolecular aggregates [1,2]. CIDS is given as the amount of light scattered when the incident beam is left circularly polarized minus that scattered when the incident beam is right circularly polarized, divided by the total amount of light scattered by the object, in our case a virus or bacterium
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