Abstract

The World Health Organization has reported about a Severe Acute Respiratory Syndrome, Coronavirus 2 (SARS-CoV2) (a virus of Wuhan, China pneumonia). The present investigation explores the transmissibility of the novel Coronavirus Disease (COVID-19) using some suitable mathematical models such as (a) a simplified Bats-Hosts-Reservoir (Wuhan Seafood Market)-People (BHRP) transmission network model useful in mapping the spread of the novel COVID-19 from its source (may be bats) to humans, (b) a concise baseline model based on individual behavioral response and control measures taken to control the transmission of the novel COVID-19 and (c) an exponential and the Susceptible-Infected-Recovered (SIR) models to predict the transmission of the pandemic on day-to-day basis. The basic Reproduction number (R0) (for the next generation matrix) was derived to estimate the transmission of the novel COVID-19 using the simplified BHRP transmission network model. The logic estimates that around 2.30 persons could be affected by the reservoir and around 3.58 persons could be affected by the community (individual person to community population). On the other hand, the concise model based on real-time time-dependent data, such as day-to-day number of tests, appreciates the initiatives (control measures) of the Chinese government to break the transmission chain of the pandemic in the capital city of Hubei province. Furthermore, the basic Reproduction number (R0) for India is reviewed to be in the range between 1.4 and 3.9 using the classical SIR model and thus, the transmission rate is the same as that of California and Washington. The review also outlines the epidemiological SIR model (based on real-time time-dependent data) which estimates about the equilibrium stage of the pandemic by the last week of May, 2020. The predictions of the age-structured epidemiological SIR model could be more accurate if data such as day-to-day number of tests are correctly fed during evaluation of the results. The present investigation emphasizes over the need of effective implementation of mitigatory strategies such as social distancing to prevent the transmission of the SARS-CoV2 outbreak in India.

Highlights

  • The novel Coronavirus (COVID-19) pandemic found its way from Wuhan Seafood Market, China (WHO, 2020a) and the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) has spread across the globe

  • The present review aims to explore the efficient mathematical modeling such as (a) the simplified Bats-HostsReservoir (Wuhan Seafood Market)-People (BHRP) transmission network model, (b) a concise baseline model based on individual behavioral response and control measures and (c) an exponential and Susceptible-Infected-Recovered (SIR) models for indepth understanding of the transmission of outbreak of the novel Coronavirus Disease (COVID-19)

  • Lin et al (2020) considered three different cases such as (a) when the government was not taking the outbreak of the novel COVID-19 pandemic seriously ( = 0) and there was no individual behavioral response (k = 0), (b) when people were aware about the novel COVID19 and (c) when the government was on alert mode with all its task forces in action to prevent the spread and the individual behavioral response reduced the cases of the novel COVID-19 patients (Fig. 4)

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Summary

Introduction

The novel Coronavirus (COVID-19) pandemic found its way from Wuhan Seafood Market, China (WHO, 2020a) and the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) has spread across the globe. The present review aims to explore the efficient mathematical modeling such as (a) the simplified Bats-HostsReservoir (Wuhan Seafood Market)-People (BHRP) transmission network model, (b) a concise baseline model based on individual behavioral response and control measures and (c) an exponential and Susceptible-Infected-Recovered (SIR) models for indepth understanding of the transmission of outbreak of the novel Coronavirus Disease (COVID-19). The transmission network model was based on the fact that SARSCoV2 was carried from infected bats (IB) Fig. 1a to some wild animals, or infected hosts (IH), who were killed and sold in Wuhan Seafood Market, China (reservoir of the novel COVID-19) and shortly thereafter, people got infected from the SARS-CoV2 (Chen et al, 2019). NP where, the term c was used as the coefficient of relative shedding of AP with respect to IP

P PeP
P P mP P mP
Dec 12
21 Mar 26 Mar 31 Mar 05 Apr 10 Apr 15 Apr 20 Apr
Mar 3 Apr 3 May 2 Jun 2 Jul 1 Aug 31 Aug
Conclusion
Findings
Conflicts of Interest

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