Abstract
Zinc is one of the essential trace elements in the human body and plays an extremely important role in physiological processes. Therefore, it is necessary to develop a detection method that can be used for real-time, highly sensitive response of Zn2+ in organisms and has low toxicity. In this work, a novel fluorescent probe NA for Zn2+ detection based on 1,8-naphthalene dicarboxylic anhydride and dimethylpyridine amine was synthesized. Probe NA has specific recognition and real-time monitoring functions for Zn2+. Based on Job's plotting curve, it is inferred that the coordination ratio between probe NA and Zn2+ is 3:1, forming a complex of [Zn(NA)3]2+. The [Zn(NA)3]2+ exhibits obvious yellow fluorescence at 550 nm. Probe NA can achieve quantitative detection of Zn2+ with a detection limit of 7.52 × 10−9 M, with high selectivity and anti-interference ability. Probe NA can stably exist in a wide pH range (2–10). This indicates that it can detect Zn2+ in complex environments. In addition, based on the low cytotoxicity, high sensitivity, and real-time monitoring characteristics of probe NA, we have expanded it to real-time monitoring of Zn2+ in organisms (HUVEC cells and live mice), as well as qualitative and quantitative detection of Zn2+ concentration in food and drugs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Photochemistry & Photobiology, A: Chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
