Abstract
Background Subacute sclerosing panencephalitis (SSPE) is a rare and severe long-term complication of measles. Hallmarks of this entity include progressive cognitive decline, myoclonia, a generalized periodic pattern on EEG and deep white matter abnormalities on MRI. However, imaging can be normal in early stages. Aim We report herein the case of a previously healthy 13-years-old girl with an unusual radiological presentation. Results She presented with unilateral myoclonia, cognitive decline with memory impairment and a first brain MRI with swelling of both hippocampi mimicking limbic encephalitis. Measles antibodies were positive in CSF and the EEG showed slow periodic complexes. Conclusion This unusual radiological presentation has never been described in SSPE. Relationship between virus and limbic system are discussed.
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