Abstract
1. The assessment of urine calcium excretion rate, serum iPTH, and 1,25(OH)2 vitamin D3 is essential in the approach to hypercalcemia. 2. Subcutaneous fat necrosis with hypercalcemia and medullary nephrocalcinosis. 3. Ectopic production of 1,25(OH)2 vitamin D3 by the infiltrated macrophage in the necrotic fat tissue. 4. Volume expansion, loop diuretics, and potassium citrate are the mainstay treatments for normalizing serum calcium and preventing further calcium deposition in the kidney. Prednisolone can be used as an alternative in refractory cases.
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