Abstract
he present study was carried out to evaluate the antifungal activity of tenselected plant extracts of Nelumbo nucifera,Senna auriculata, Salvia officinalis, Tagetes erecta,Psidium guajava,Argemone mexicana,Hibiscussabdariffa, Hemidesmus indicus, Moringa oleifera,andGlycyrrhizaglabrawith ketoconazole as the positive reference standard. Their antimalassezial efficacy was tested using different concentrations of extracts in various solvents. The preliminary screening of plant extracts was determined by Kirby Bauer disc diffusion method and among the tenplantextracts, aqueous extract of S.officinalisand ethanol extract of H.sabdariffaextract exhibited potent antifungal activity against Malasseziafurfur. The purification and partial characterization of H. sabdariffa and S.officinalis were carriedout by Thin layer chromatography (TLC) technique.The Minimum Inhibitory Concentration (MIC) of H.sabdariffa andS.officinalisagainst M. furfur by Kirby Bauer method was0.312mg/mLand 0.625mg/mLrespectively against 50 μg/mLof Ketoconazole which was used as the standard. The phytochemical analysis of S.officinalis and H.sabdariffa revealed the presence of terpenoids, steroids, tannins, and polyphenols of which the concentration of polyphenols and flavonoids were significantly higher in S.officinalisand H.sabdariffa respectively. Thus, the present study concludes that S.officinalisand H.sabdariffa havea potent activity against M. furfur, thereby reducing the prevalence of dandruff, provided the future perspectives of the study that includecharacterization and cytotoxicity of the compound.©2022Caproslaxy Media. All rights reserved.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
