An indication of possible impending toxicity during moderately high dose methotrexate infusions.

Abstract

British Journal of Clinical PharmacologyVolume 6, Issue 6 p. 551-552 Free Access An indication of possible impending toxicity during moderately high dose methotrexate infusions. JW Paxton, JW PaxtonSearch for more papers by this authorEJ Stephens, EJ StephensSearch for more papers by this authorHF Wood, HF WoodSearch for more papers by this author JW Paxton, JW PaxtonSearch for more papers by this authorEJ Stephens, EJ StephensSearch for more papers by this authorHF Wood, HF WoodSearch for more papers by this author First published: December 1978 https://doi.org/10.1111/j.1365-2125.1978.tb00887.xCitations: 3AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. References Bender, J.F., Grove, W.R. & Fortner, C.L. (1977). High-dose methotrexate with folinic acid rescue. Am. J. Hosp. Pharm., 34, 961– 965. Djerassi, I., Kim, Sun J., Nayak, N., Ohanissian, H., Adler, S. & Hsieh, S. (1977). New ‘Rescue’ with massive doses of citrovorum factor for potentially lethal Methotrexate toxicity. Cancer Treat. Rep., 61, 749– 750. Jaffe, N., Frei, E., Traggis, D., Cassady, J.R., Watts, H. & Filler, R.M. (1977). High-dose methotrexate with citrovorum factor in osteogenic sarcoma. Cancer Treat. Rep., 61, 675– 679. Nirenberg, A., Mosende, C., Mehta, B.M., Gisolfi, A.L. & Rosen, G. (1977). High-dose methotrexate with citrovorum factor rescue: Predictive value of serum methotrexate concentrations and corrective measures to avert toxicity. Cancer Treat. Rep., 61, 779– 783. Paxton, J.W. & Rowell, F.J. (1977). A rapid, sensitive and specific radioimmunoassay for Methotrexate. Clinica Chim. Acta, 80, 563– 572. Pinedo, H.M. & Chabner, B.A.(1977). Role of drug concentration, duration of exposure in determining methotrexate cytotoxicity. Cancer Treat. Rep., 61, 709– 715. Pratt, C.B., Roberts, D., Shanks, E. & Warmath, E.L. (1975). Response, toxicity and pharmacokinetics of high-dose methotrexate (NSC-740) with citrovorum factor (NSC-3590) rescue for children with osteosarcoma and other malignant tumours. Cancer Chemother. Rep., 6, 13– 17. Rosen, G., Ghavimi, F., Nirenberg, A., Mosende, C. & Mehta, B.M. (1977). High-dose methotrexate with citrovorum factor rescue for the treatment of central nervous system tumours in children. Cancer Treat. Rep., 61, 681– 690. Salasoo, S., Irving, M.G., Lam-Po-Tang, R., O'Gorman-Hughes, D. & Freedman, A. (1976). Methotrexate megadose followed by folate rescue 1. A study in clearance patterns. Med. J. Aust, 1, 777– 779. Tornyos, K. & Faust, H. (1978). Oral high-dose methotrexate with citrovorum factor rescue in metastatic squamous cell carcinoma of the lung. Cancer, 41, 400– 402. Turman, S., Coleman, M., Silver, R.T. & Pasmantier, M. (1977). High-dose methotrexate with citrovorum factor in adult resistant lymphoma. Cancer, 40, 2823– 2828. Citing Literature Volume6, Issue6December 1978Pages 551-552 ReferencesRelatedInformation