An Inappropriate ADH Syndrome and Lung Cancer Diagnosis in A Patient with Isolated Hyponatremia

Abstract

Hyponatremia is generally considered to have a plasma sodium concentration less than 135 mEq / L.It is the most common electrolyte abnormality which is important in clinical practice. It can be caused by many etiological factors. İnappropriate antidiuretic hormone syndrome (SIADH) is the one of the causes of normovolemic hyponatremia. On the other hand SIADH is responsible for 30% of hyponatremias due to cancer. It appears as a paraneoplastic syndrome especially and most offen in the lung carcinoma. The World Health Organization (WHO) reported that lung cancer is 12.9% of all cancers. It may manifest itself with specific symptoms, but may also show only the paraneplastic syndrome. Therefore, it should be kept in mind that the cause of hyponatremia must be determined and may be a symptom of SIADH and lung cancer.