Abstract

Several electron microscopic studies have shown that in some types of cells allowed to undergo necrosis on exposure to various injurious agents, there are discrete and predictable alterations in ultrastructure. In crayfish nerve cords exposed to in vitro anoxic conditions, necrosis also proceeds in an orderly manner. These changes are characterized by alterations in Schwann cell morphology occurring shortly before discernable changes in the axon proper.Ventral nerve cords of the crayfish (Procambarus clarkii) were dissected, divided into control and experimental portions after tieing the ends with thread, and mounted in covered plastic Petri dishes which contained 50 ml.

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