Abstract
Though metal ions are essential components of many cellular functions, their overexposure to organisms lead to oxidative stress through the formation of reactive oxygen species (ROS). Lipid peroxidation (LPX) is the oxidative deterioration of membrane lipids and considered as an index of oxidative stress. In the present study in vitro effect of various metals (FeCl3, FeSO4, CuSO4, CdCl2, and ZnSO4) on the lipid peroxidation of gills and hepatopancreas of Giant Freshwater prawn, Macrobrachium rosenbergii, was compared with respect to dose and duration. The results clearly indicate that among all the metals investigated, FeCl3 and CdCl2 are more potent in inducing LPX, and FeCl3 is more toxic than FeSO4 in inducing LPX in the hepatopancreas. ZnSO4 exhibits a moderate toxicity while CuSO4 is least toxic and also inhibits LPX at higher concentration. Thus results of the present investigation suggest that all the metal ions investigated in the present study are capable of inducing oxidative stress in gills and hepatopancreas of M. rosenbergii
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