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Abstract
Objectives: The incomplete endothelialization of mainly small caliber vascular prostheses is a major drawback in cardiovascular surgeries. The lack of an endothelium leads to the occurance of thrombosis at the luminal surface of artificial vascular prostheses. The generation of a fully functional endothelium on the surface of blood contacting devices is a promising approach in terms of the improvement of hemocompatibility and the maintenance of long term graft patency. We present a low-cost in vitro rotation model composed of disposables for investigation of endothelialization of artificial surfaces.
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