Abstract
Bacterial meningitis is a devastating disease with high mortality rates of up to 25% leading to life-long disabilities in up to 50% of the survivors. Brain injury caused by bacterial meningitis prominently affects the cortex and hippocampus a brain region involved in learning and memory function. In experimental bacterial meningitis hippocampal injury is characterized by apoptotic cell death of neuronal stem cells and/or their progeny in the subgranular zone of the dentate gyrus, which is responsible for neurogenesis, and therefore potentially well equipped for brain repair.
Highlights
Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.
Bacterial meningitis is a devastating disease with high mortality rates of up to 25% leading to life-long disabilities in up to 50% of the survivors
Brain injury caused by bacterial meningitis prominently affects the cortex and hippocampus a brain region involved in learning and memory function
Summary
Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. . An in vitro model of central nervous system infections and regeneration: neuronal stem cells as regenerative therapies in bacterial meningitis Address: Institute for Infectious Diseases, University of Bern, Bern, 3010, Switzerland
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
