An In- Silico Studies for Immunomodulatory Potential of Phytoconstituents from a Naturally Occurring Herb Nigella Sativa

Abstract

Nigella sativa L. belongs to the family of Ranunculaceae, commonly known as Black Cumin or Kalonji. It is an annual herb used as a food ingredient and spice. N. Sativa is approved by the US Food and Drug Administration (FDA) as food and by the Flavor and Extract Manufacturers Association (FEMA) as generally recognized as safe (GRAS). We aimed to identify the potent immunomodulatory phytoconstituents of N. Sativa using the in-silico studies like molecular docking. For docking assessment, two prot