Abstract

A delayed SEIRS epidemic model with pulse vaccination and saturation incidence rate is investigated. Using Krasnoselskii's fixed-point theorem, we obtain the existence of infection-free periodic solution of the impulsive delayed epidemic system. We define some new threshold values , and . Further, using the comparison theorem, we obtain the explicit formulae of and . Under the condition , the infection-free periodic solution is globally attractive, and that implies that the disease is permanent. Theoretical results show that the disease will be extinct if the vaccination rate is larger than θ* and the disease is uniformly persistent if the vaccination rate is less than θ*. Our results indicate that a long latent period of the disease or a large pulse vaccination rate will lead to eradication of the disease. Moreover, we prove that the disease will be permanent as .

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