Abstract

A facile one-step condensation of the cyclopentenyl α,-tosylate 2c with the alkali metal salts of 6-chloropurine and uracil, afforded the protected carbocyclic nucleosides 5a and 8 , respectively, which were converted to neplanocin a ( 6 ) and cyclopentenyl uracil ( 9 ) by established methods.

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