An Impact of Suspected Peritubal Adhesions by Hysterosalpingography on Outcomes of Intrauterine Insemination

Abstract

Objective To assess the fertility prospect of women with suspected peritubal adhesions diagnosed by hysterosalpingography (HSG) treated with intrauterine insemination (IUI). Methods The study group consisted of 93 patients diagnosed as bilateral suspected peritubal adhesions by HSG, and 175 patients with no tubal pathology were classified as control group. A total of 496 cycles of IUI were finished in 268 infertile women. Results There were no differences in basic clinical parameters between the two groups. Cumulative pregnancy rates after two cycles of IUI were 19.4% for the study group, and 34.3% for the control. Cumulative pregnancy rate in the women with abnormal contrast media loculation was significantly lower than that in women of the control (7.4% vs 34.3%, P=0.037). The cumulative pregnancy rates were similar between the women with abnormal tubal contour and the normal ones (36.7% vs 34.3%, P=0.800). Conclusion Suspected peritubal adhesions in HSG were worthy more attention, since the outcome of IUI in women with loculation of contrast material, combined with or without abnormal tubal contour resulted in a significantly lower pregnancy rate than the normal ones. IUI should be delayed before tubal patency was confirmed during these patients.