Abstract

Early predicting heart attack out of stroke patients in a view of data analysis is an approach to reduce a high mortality rate. Stroke-patient data in Intensive Care Unit are imbalanced due to that stroke patients with heart attack are in the minority of stroke patients. How to predict heart attack in the stroke-patient data becomes a challenge. For processing the imbalanced data, this paper designs an algorithm by leveraging random undersampling, clustering and oversampling techniques, which is called undersampling-clustering-oversampling algorithm (shortly, UCO algorithm). The UCO algorithm generates nearly balanced data which are utilized to train machine-learning models for predicting heart attack. Over the database of Medical Information Mart for Intensive Care III, extensive experiments are conducted to evaluate the UCO algorithm. A setting of undersampling number of 120 in the algorithm UCO, denoted UCO(120), shows good performance in helping machine-learning classifiers extract features. Five classifiers are separately deployed to predict heart attack based on outputs of the UCO(120). Our results show that random forest classifier achieves the best predicting performance with an $accuracy$ of 70.29%, and $precision$ of 70.05%. It could be well-predicted using UCO(120) and random forest that whether a stroke patient will have heart attack or not.

Highlights

  • Stroke, known as ‘‘ischemic stroke’’, refers to ischemic necrosis or softening of localized brain tissue caused by cerebral blood supply, ischemia and hypoxia

  • Based on the above analyses of related work, we propose a workflow for the study of heart attack prediction over stroke patients

  • Random Forest algorithm is used to predict the risk of heart attack in stroke patients

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Summary

Introduction

Known as ‘‘ischemic stroke’’, refers to ischemic necrosis or softening of localized brain tissue caused by cerebral blood supply, ischemia and hypoxia. Heart attack is a myocardial necrosis caused by acute and persistent ischemia and hypoxia of coronary artery which manifestations are arrhythmia, shock or heart failure, which can be fatal [2]. The stroke complicated by heart attack was 30%, and the mortality rate was as high as 54%[3].The main causes of death are ventricular arrhythmia, acute left heart failure and cardiogenic shock. Troponin is an effective indication to detect heart attack [4]–[6]. A drawback of troponin is that troponin starts changing just four hours after heart attack. There exists a time delay of four hours for the troponin changes that signify the happened

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