Abstract
ObjectiveTo explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). MethodsA chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. ResultsBMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than −2 at most sites. ConclusionResults suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy.
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