An Experimental Study on the Epiphyseal Infarction and Physical Stimulus of the Articular Unconformity on the Epiphyseal Cartilage

Abstract

Operation was performed on the growing rabbits of average 600 gramms weight. After the knee joint was opened by an incision, the meniscus, articular cartilage of the tibia, subchondral bone were resected, but both the proximal growth plate and the epiphyseal bone plate were left unoperated.Concluded results were as follows:In three weeks after operation over sized cells were in sight in the germinal cell layer, both proliferation and normal maturation of the cells of the growth plate were slowed and the cartilage increased in thickness. In four weeks after operation many germinal cells degenerated under the influence of either a physical stimulus of the articular unconformity and the incomplete revascuralization, devided and proliferated to the granulation in the articular space.