Abstract
SUMMARY The cardiovascular actions of suxamethonium were studied in spinal cat preparations, and in cats with intact central nervous systems anaesthetized with a thiopentone, nitrous-oxide and oxygen sequence. Mechanical artificial ventilation of the lungs was maintained throughout. Intra-arterial pressure, standard limb lead electrocardiograms and respiratory movements were recorded. Under these conditions suxamethonium was shown to have nicotine-like and muscarine-like activity. It is suggested that suxamethonium produces similar effects in other animals and in man.
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