Abstract
Numerical simulations of arterial walls allow a better understanding of the interaction between biological tissue and endoprosthesis ( stents ), which are used in aneurysms or atherosclerosis stenosis treatment. A reliable understanding of this interaction may help one to select, or even design, the best structure for a given clinical indication. The development of a realistic numerical simulation requires an appropriated definition of a constitutive model and the obtainment of experimental data useful to a parameter identification procedure. Biological tissues have different mechanical characteristics of materials commonly used for engineering applications, however the experimental data acquisition is a major challenge. Some examples of technical difficulties of experimental test in biological tissue are associated to the obtainment of samples, temperature and humidity control during storage, suitable gripping and geometric and strain measurements methods. Therefore, this paper presents an experimental methodology to perform uniaxial mechanical tests in pig arteries in order to provide useful information for material models of arterial walls. This study proposes the experimental procedure from the sample obtainment to the uniaxial experimental testing of the tissue in two directions (circumferential and longitudinal) at two strain rates. In order to shown the use of the experimental data into a suitable numerical model for arterial walls, a parameter identification procedure was performed to obtain material parameters of a viscoelastic anisotropic model with fiber dispersion for finite strains. Through the experimental methodology proposed it was possible to obtain useful data for the parameter identification. Moreover, the results demonstrate that the arterial walls mechanical behavior was properly represented by the selected model.
Highlights
Arteries are blood vessels that carry blood from heart to all parts of the body, carrying nutrients and oxygen (JUNQUEIRA, 2004)
Numerical simulations of arterial walls allow a better understanding of the interaction between biological tissue and endoprosthesis, which are used in aneurysms or atherosclerosis stenosis treatment
These pathologies can be treated by the use of vascular endoprosthesis, which are inserted through surgical interventions
Summary
Arteries are blood vessels that carry blood from heart to all parts of the body, carrying nutrients and oxygen (JUNQUEIRA, 2004). The arteries can be divided into elastic and muscular, possessing collagen and elastin as their main constituents, which alongside with other components, are arranged in layers. These layers should provide mechanical strength to stand vessels internal pressures. Arteries are subject to several pathologies and the major ones are atherosclerosis and aneurysm. These pathologies can be treated by the use of vascular endoprosthesis (stents), which are inserted through surgical interventions. The use of stents for pathologies correction can trigger adverse events that may require further surgery intervention. Some of the possible problems are: leakage, device displacement (migration), implant rupture, or arterial wall tissue damage (BLUM et al, 2001, JACOBS et al, 2003, LI et al, 2006, CORBETT et al, 2008, BOCK et al, 2012, MORRIS et al, 2013)
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