Abstract
Background:Karavellaka Phalaalso advocated for treatment of Krimi in various texts which are coated in various Nighantu such as Bhavaprakasha Nighantu. Hence, KaravellakaPhala can be used as antimicrobial agent in the place of antibiotics.Aims and Objectives: The objective of this study was (1) to evaluate Krimighna (Antimicrobial) effect of aqueous and alcoholic extract of Karavellaka Phala and (2) to compare antimicrobial action of test drug with standard drug group.Materials and Methods: The methodology followed in the present study encompasses the following aspects: (1) microscopic and macroscopic study of Karavellaka Phala, (2) phytochemical analysis of Karavellaka Phala,(3) preparation of test drug extracts with disk diffusion method, and (4) screening of anti-microbial activity of Karavellaka Phala. (a) 1 Gram-positive bacteria = Staphylococcus aureus, (b) Gram-negative bacteria = Klebsiella pneumonia, and (c) Standard Drug Group – Amoxicillin.Observation and Results: After incubated at 37C for 48 h, the zone of inhibition was measured in mm for each organism with different extracts to evaluate anti-microbial activity of Karavellaka Phala.
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