Abstract
Background and objective: In India Medicinal plants have a wide range of uses in folk medical practice. An- drographis macrobotrys Nees. belongs to Acanthaceae family is found in South India and Srilanka. It is in folk use by tribes in Kerala to treat muscle pain, snakebite, fever, and jaundice. The present research work aims to evaluate test drugs for their analgesic action. Methods: The detailed review of the test drug and disease Pain has been carried out. An animal experimental study has been carried out to assess the analgesic activity of the drug by acetic acid- induced writhing movement in Swiss albino mice and Eddy’s hot plate method in Wistar albino rats. Results and conclusion: The test drug showed analgesic action with Swarasa of leaves and Kashaya of the whole plant. The drug was found to have both peripheral and central analgesic action. Keywords: Andrographis macrobotrys Nees., Acanthaceae, folk medicinal plant, Analgesic action
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