Abstract
An expeditious synthesis of 4H-chromenes has been achieved by three-component one-pot condensation of 1,3-diketone, aldehyde, and malononitrile using Ba(OTf)2 as catalyst in PEG-water at room temperature. Results from various reaction media and different metal triflates as catalysts show that choice of proper catalyst and the solvent system play a key role in the synthesis of 4H-chromene-3-carbonitrile derivatives. The catalyst can be recovered and reused at least five times without loss of activity. The application of an eco-friendly, noncorrosive, and reusable catalytic system with high isolated yield of the products makes this method advantageous.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
