An expedient and efficient chemoselective protection of carbonyl compounds and transthioacetalization of O, O- and S, O-acetals catalyzed by HBF 4-SiO 2

Abstract

Trace amount of solid-supported fluoroboric acid (HBF 4-SiO 2) was found to be an effective catalyst for chemoselective and highly efficient protection of carbonyl compounds and transthioacetalization of O, O- and S, O-acetals under solvent-free conditions. Moreover, the catalyst can be recycled for number of times without significant loss of activity.