Abstract

One-hundred extracted human single-rooted teethwere biomechanically instrumented. Sixty teeth were obturated with gutta-percha and three types of root canal cements, which were Roth Root Canal Cement, Calciobiotic Root Canal Sealer, and Sealapex. None of the remaining 40 teeth (controls) were obturated; however, 20 had their apical foramina sealed and the other 20 had patent foramina. Five microliters of [3H]uridine were deposited into the prepared root canal of each tooth, and radioisotope counts were obtained at various intervals postoperatively (2 to 60 days). The results showed that there was no statistical difference in leakage between the obturated groups and the sealed control group; however, when compared with the control group with patent foramina there was a significant difference. One-hundred extracted human single-rooted teethwere biomechanically instrumented. Sixty teeth were obturated with gutta-percha and three types of root canal cements, which were Roth Root Canal Cement, Calciobiotic Root Canal Sealer, and Sealapex. None of the remaining 40 teeth (controls) were obturated; however, 20 had their apical foramina sealed and the other 20 had patent foramina. Five microliters of [3H]uridine were deposited into the prepared root canal of each tooth, and radioisotope counts were obtained at various intervals postoperatively (2 to 60 days). The results showed that there was no statistical difference in leakage between the obturated groups and the sealed control group; however, when compared with the control group with patent foramina there was a significant difference.

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