Abstract

Of 159 patients being investigated at the infertility clinic during 1978, 31 agreed to undergo than human chorionic gonadotrophin (HCG) stimulation test. Twenty-one of these patients exhibited varying degrees of oligozoospermia and their response to HCG, measured by a rise in serum testosterone, was not significantly different from that of the remaining patients who had normal sperm counts. Endocrine function of the testes appears to be unaltered even in patients with severely impaired tubular function. It is concluded that assessment of Leydig cell function is of no value in the routine investigation of male fertility.

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