Abstract

The term Myalgic Encephalomyelitis (ME) was initially used in the 1950s [1]. ME describes a syndrome where there is general muscle pain associated with evidence of a disturbed nervous system [2]. ME, commonly referred to as Chronic Fatigue Syndrome (CFS), or post-viral fatigue syndrome is a condition in which mental and physical fatigue predominate. It is characterized by gross abnormal muscle fatigue which occurs after relatively mild activity. Other symptoms regularly complained of include sleep disturbance, headaches, cognitive dysfunction, feeling depressed, bouts of low grade fever (not exceeding 38-6°C), increased sensitivity to light, back and neck pain, sore throat, irritable bowel and bladder [3]. The symptoms of ME typically become apparent following a viral infection [4], although other trigger factors have been noted. Vaccinations against cholera, tetanus, typhoid and influenza have been associated with the onset of ME [5]. It has also been observed that any psychological disturbances in ME occur secondary to, or share a common pathophysiology with an immunological dysfunction [6]. In many cases there appears to be no apparent triggering factor [7].

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