Abstract

Background:Despite cardiovascular diseases and cancer being the leading causes of premature mortality in the Caribbean region, there is limited local research available to guide a comprehensive response to this epidemic.Objective:To evaluate cardiovascular disease and cancer research in the Caribbean using abstracts presented at the Caribbean Public Health Agency’s (CARPHA) meeting – the longest running annual research conference in the region.Method:Study data (population, intervention/exposure, comparison and outcome) were extracted from abstracts published for the 2006 to 2018 meetings. Additionally, institutional affiliation and geographic location of the first author, countries involved, sample size, study design and use of specialized testing/biomarkers were also extracted. Data were analysed using STATA version 14.Findings:A total of 1,512 abstracts, 728 posters and 784 oral presentations were reviewed. Research on cancer and cardiovascular disease comprised approximately 15% of all abstracts published annually over the review period. Most of the cardiovascular disease studies had cross sectional or survey designs (46%), with very few laboratory-based studies (<2%) and no intervention studies/clinical trials. For cancer research, 30% were cross-sectional studies/audits, 11% were case control studies, 5% were lab based and there were no clinical trials. Almost a quarter of the cardiovascular disease / cancer abstracts over the period originated from Trinidad and Tobago (26%), with Jamaica and Barbados contributing 18% and 15% respectively.Conclusion:These finding highlight the need for additional studies that can provide evidence for interventions and policy to address the region’s high cardiovascular disease and cancer burden. A Regional Centre of Research Excellence could support capacity development to facilitate this process.

Highlights

  • Almost a quarter of the cardiovascular disease / cancer abstracts over the period originated from Trinidad and Tobago (26%), with Jamaica and Barbados contributing 18% and 15% respectively. These finding highlight the need for additional studies that can provide evidence for interventions and policy to address the region’s high cardiovascular disease and cancer burden

  • The epidemiologic transition in disease patterns in the Caribbean started during the 1960s, with a shift in the majority of deaths resulting from malnutrition and infectious diseases in the 1950s to Non-communicable diseases (NCD) by the early 1970s [3]

  • The Declaration signed by the Caribbean Community (CARICOM) Heads of Government pledged to tackle the region’s NCD epidemic through a series of strategies and policies

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Summary

Introduction

The Declaration signed by the Caribbean Community (CARICOM) Heads of Government pledged to tackle the region’s NCD epidemic through a series of strategies and policies This initiative led to the 2011 United Nations High Level Meeting on NCDs and helped to shape the global NCD agenda [5]. Despite this laudable achievement, the Caribbean has lagged in research initiatives to find solutions to the growing NCD burden [6]. Despite cardiovascular diseases and cancer being the leading causes of premature mortality in the Caribbean region, there is limited local research available to guide a comprehensive response to this epidemic

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