Abstract
BackgroundThe present study investigated the effect of peforelin (Maprelin®), a gonadotropin-releasing hormone (GnRH) analogue, administration in gilts, primiparous and pluriparous sows in a high productive farm on sow reproductive performance and piglet quality at birth.MethodsIn a 400 sow herd, gilts, primiparous and pluriparous sows were randomly allocated to 2 groups: peforelin treated (peforelin = P-group) or no treatment (control = C-group). Animals were injected 48 h after the last altrenogest treatment (gilts) or 24 h post weaning (sows). Weaning-to-estrus interval (WEI), estrus rate (ER), farrowing efficiency index (FEI), farrowing rate (FR), number of total (TBP), live (LBP) and stillborn piglets (SBP), mummies (MM) and live piglet index (LPI) were assessed and compared between treatment groups. To assess piglet quality at birth, 6033 piglets from 426 litters were weighed individually within 24 h after birth (BW; birth weight).ResultsNo significant difference between treatment groups could be observed for WEI, TBP, LBP, SBP and MM. The ER was significantly (P = 0.0119) higher (93.2 %) in the P-group as compared to the C-group (87.2 %). Peforelin treatment did not affect farrowing rate. Both FEI and LPI were significantly (P = 0.0078) better in the P-group as compared to the C-group. Overall, no effect of peforelin treatment on piglet birth weight could be observed, although specific subcategories (1st parity and older (5+ parity) sows) did have a significant impact of treatment on birth weight. During late summer (August-September) all treated gilts and sows took advantage from peforelin treatment with a significant improvement of piglet birth weight.ConclusionPeforelin treatment had a significant impact on ER, FEI and LPI. Moreover, piglet birth weight improved for specific sow subcategories (1st parity and older sows) and for all gilts and sows during the late summer infertility period.
Highlights
The present study investigated the effect of peforelin (Maprelin®), a gonadotropin-releasing hormone (GnRH) analogue, administration in gilts, primiparous and pluriparous sows in a high productive farm on sow reproductive performance and piglet quality at birth
Peforelin treatment had a significant impact on estrus rate (ER), farrowing efficiency index (FEI) and live piglet index (LPI)
Piglet birth weight improved for specific sow subcategories (1st parity and older sows) and for all gilts and sows during the late summer infertility period
Summary
The present study investigated the effect of peforelin (Maprelin®), a gonadotropin-releasing hormone (GnRH) analogue, administration in gilts, primiparous and pluriparous sows in a high productive farm on sow reproductive performance and piglet quality at birth. Recent evidence has shown that reproductive performance is influenced by wean-to-estrus (WEI) interval [26]. Pharmaceuticals, such as progesterone-analogues and gonadotropins, are used in practice to control reproduction with the aim to increase the reproductive performance of gilts and sows [8]. Natural gonadotropin secretion is controlled through the release of hypothalamic peptides, gonadotrophinreleasing hormones (GnRH), which pass through the hypophyseal portal vessels to the pituitary gonadotrophs, causing the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) [22]. GnRH regulates both FSH, playing a key role in growth and maturation, and LH to a certain extent, with final ovulation of the follicles [5, 21]
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