Abstract

A number of exploratory experiments produced results that suggested a simplified method of producing suppression of kindled behavior by 1-Hz sine-wave stimulation. This method involved determining the effective threshold intensity to produce kindled behavior (ETI1), followed 1 h later by stimulation with 1-Hz sine waves at the ETI1 intensity for 5 min. Three hours later, a second 1-Hz trial occurred. Eighteen hours later, ETI2 was determined. Four experiments with this method indicated clearly its effectiveness. However, when contrasted with the previous method used (a 1-60-1 sequence over a number of days with an intertrial interval of 1 h) both methods were equally effective.

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