An etiological analysis of Chinese neuro-ophthalmology disorders in child and adolescent inpatients

Abstract

Objective To investigate the etiology of pediatric neuro-ophthalmology disorders in China.Methods Retrospective case series.Clinical data of children and adolescents ＜18 years suffered from neuro-ophthalmology diseases who hospitalized in the Department of Neuro-ophthalmology,General Hospital of PLA from October 2009 to July 2011 was reviewed.Results Totally 129patients were recruited to study.The visual afferent system of 120 cases was injured including 93cases with optic neuropathy,which accounted for 77.50％ of the patients with visual afferent system injured and 72.09％ of the total hospitalized patients.The efferent nerve system of 13 cases was injured.The ocular motor system was affected in 9 cases,which accounted for 69.23％ of the patients with efferent nerve system affected and 6.98％ of the total hospitalized patients.Unilateral eye was affected in 53 cases,and bilateral eyes were affected in 76 cases,involving a total of 205 eyes,118 cases (91.47％) were identified the original reasons.There were optic neuritis (33 cases),traumatic neuropathy (30 cases),congenital or hereditary optic neuropathy (18 cases),brain tumor or intracranial compressive disorder (14 cases),infectious disease (8 cases),vascular diseases (5 cases),myasthemia gravis (3 cases),psychogenic hypopsia (2 cases),idiopathic intracranial hypertension (2 cases),inflammatory disease (2 cases),Adie's syndrome (1 case),and idiopathic oculomotor nerve palsy (1 case).Conclusions Optic neuropathy is the most common disorder in neuro-ophthalmology in child and adolescent inpatients.Optic neuritis,traumatic optic neuropathy and congenital or hereditary optic neuropathy are major causes for optic neuropathy. Key words: Neuro-ophthalmology; Etiological analysis; Children and adolescents