Abstract

A good many years ago my interest in the history of this book was aroused by K. Mendel's statement in his monograph on paralysis agitans to the effect that, notwithstanding his thorough search through the libraries of the German universities, as well as through the Royal Library, and through the larger English libraries, he did not succeed in finding one copy of Parkinson's original description of the disease contained in an octavo booklet, entitled An Essay on the Shaking Palsy, published in 1817 by Sherwood, Nelly & Jones, London. Charcot in his twentieth Lecon de Mardi, given on June 12, 1888, in his clinic at La Salpetriere, said that it was only after a long search that he was able, through the kindness of the librarian of the University of Manchester, to see and read a copy of this little book. On that morning he advised his students to translate

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