Abstract

A virus (Sakai) which had been recovered from an outbreak of disease in horses was found to be a small spherical enveloped RNA virus with a diameter of approximately 70 nm and a buoyant density of 1·22 g per ml. It grew well and produced a cytopathic effect in a variety of cell cultures; it was sensitive to organic solvents, heat and low pH. It agglutinated goose erythrocytes in a 0·35 M sodium chloride solution at an optimum pH of 6·2 and was antigenically identical or closely related to Getah virus, a member of the alphavirus subgroup of the Togaviridae.

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